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MiniStage for Next Generation Sequencing

MiniStage Sequencing
Next Generation Sequencing (NGS) systems enable the sequencing of millions of DNA molecules simultaneously. These powerful tools are revolutionizing fields such as personalized medicine, genomics, genetic diseases, biomedical research and clinical diagnostics, by offering a high throughput option with the capability to sequence multiple individuals at the same time.

While different NGS platforms may differ in technical details, they all feature the following elements:

• Sample preparation;
• The sequencing machine;
• Data generation.

Precision linear motion is used in both sample prep and the actual sequencing cycle.

Application Challenges:

• High resolution for fine positioning.
• High stiffness for vibration/noise reduction.
• Compact size for small footprint and benchtop machines.

Typical Current Motion Solutions:

• Compact linear rails
• Lead screws with stepper motors
• MiniStage

HKP’s MiniStage Combines a Hybrid Actuator, Lead Screw and Guide Rail into a Compact, Fully Assembled & Tested Solution

MiniStage Infographic

MiniStage is the industry’s most compact motorized hybrid stepper linear rail. It combines the core AMETEK Haydon Kerk Pittman hybrid actuator and lead screw technology with the
guidance and load handling capacities of a recirculating ball bearing profile rail. Delivered as a fully assembled and tested solution from a single supplier, MiniStage saves time & money,
reduce supply chain risks, and make it easier for engineers to focus on end-product design. MiniStage’s precise linear guidance is delivered in a smaller footprint, with ultra-quiet
operation, making it an ideal solution for any application that requires accurate positioning.

Features and options available for the compact MiniStage include:

• Low-profile miniature rail for increased moment load and stiffness compared to alternatives
• Nema size 8 motor with integrated screw for reduced overall length
• Mounting flexibility and system stiffness through baseplate
• Several screw lead / resolution options
• Several rotary encoder options
• Optional anti-backlash nut.

Hybrid Stepper Linear ActuatorSize 8: 21 mm (0.8-in) (1.8° Step Angle)
Wiring
Bipolar
Winding Voltage 2.5 VDC 5 VDC 7.5 VDC
Current (RMS)/phase .49 A .24 A .16 A
Resistance/phase 5.1 Ω 20.4 Ω 45.9 Ω
Inductance/phase 1.5 mH 5.0 mH 11.7 mH
Power Consumption 2.45 W
Rotor Inertia 1.4 gcm2
Insulation Class Class B(Class F available)
Weight 1.5 oz (43 g)
Insulation Resistance 20 MΩ

MiniStage Load Specifications
Design Payload (mass)
3.6kg [8 lbs]
Axial Force 45N [10 lbf]
Roll Moment* 1.13N-m [10 lbf-in]
Pitch Moment* 1.13N-m [10 lbf-in]
Yaw Moment* 0.9N-m [8 lbf-in]
Repeatability +/-25µm [0.001 in]


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